For 60 years, COMBER has been a leading supplier of Nutsche filters, pressure filter dryers and batch type vacuum dryers for pharmaceutical and chemical production. It is indeed from 1960 that COMBER, now part of part of HEINKEL Drying and Separation Group (HDSG), offers its customers high quality machinery, all Made in Italy.
For the manufacture of sterile parenterals, i.e. substances which are intended for injection, infusion or implantation into the human or animal body, the issue of sterilization of process equipment is of high priority. In addition to a local cleaning of a process plant, also known as Clean in Place (CIP), many pharmaceutical processes require therefore a subsequent sterilization (sterilization in place). For example this can be ensured by steam sterilization. In this respect all product contacted surfaces should be coated safely and for a defined period with pressurized steam of at least 121 °C.
HEINKEL has optimised system and machine control. The corresponding HMI panels work with the S7 TIA control system from Siemens and thus facilitate the operation of centrifuges, (filter) dryers and mixers of both the corporate HEINKEL, BOLZ-SUMMIX and COMBER brands and third-party makes.
In the field of mechanical and thermal separation, the HEINKEL Group often uses mechanical seals besides shaft seals and stuffing boxes. For the manufacturing of API (Active pharmaceutical ingredients) and fine chemicals, usually non contacting, gas lubricated (lift-off) mechanical seals are used. In the field of horizontal dryers, this solution which prevents cross contamination is increasingly applied by COMBER customers who prefer inert gases as a lubricant.